ENTERPRISE THERAPEUTICS LTD

SUSSEX INNOVATION CENTRE SCIENCE PARK SQUARE, FALMER, BRIGHTON, BN1 9SB

Company Number: 09022750
Incorporation date: 02-May-2014
Status: Active
Entity type: Private Limited Company

SIC codes:
72110 Research and experimental development on biotechnology

SUMMARY

This company is 11.1 years old and is currently active. It is controlled by multiple entities. Retained earnings is negative (GBP -88.3 million), which means the company has aggregate losses since it's inception or it has paid more dividends than it can afford; given the company's age, this is a sign of serious financial problems. The company has 1 active officers (directors or partners) who are or were officers of 7 other companies. The company has no public disputes filed on the Business Disputes Register. There are no court cases involving the company that we are aware of.

FINANCIALS (BETA)

Next accounts due: 30-Sep-2025
Accounts Filed: FULL (31-Dec-2023)

P&L Financials:

Year end	Currency	Revenue	Operating profit	Interest Received	Interest Paid	Tax	Net Profit GBP
31-Dec-2024	GBP		-7,584,264	368,596		756,527	-7,215,668
31-Dec-2023	GBP		-3,931,787	43,944		961,089	-3,887,843
31-Dec-2021	GBP	1,225,413	-4,191,175	1,386		1,328,615	-4,189,789
31-Dec-2020	GBP	1,077,612	-5,892,234	28,966	2,719	1,921,500	-5,863,268
31-Dec-2019	GBP		-7,775,885	151,501	2,807	1,259,037	-7,627,190
31-Dec-2018	GBP	90,968		17,039	402		-4,961,193
31-Dec-2017	GBP	83,168	-3,941,813	15	1,437		-2,328,637

Balance Sheet Financials:

Year end	Currency	Cash	Current Assets	Current Liabilities	Share Capital	Premium Reserve	Retained Earnings	Net Assets
31-Dec-2024	GBP	6,714,252	10,400,640	23,428,824	318	62,319,246	-88,283,540
31-Dec-2023	GBP	1,501,571	2,949,273	8,732,509	477	93,478,869	-143,816,565	17,298,960
01-Jan-2023	GBP				159	31,159,623		-1,878,477
31-Dec-2021	GBP	1,637,365	3,220,540	435,394	318	62,319,246	-58,480,350
31-Dec-2020	GBP	1,821,342	7,018,901	227,497	477	93,478,869	-94,338,276	18,328,188
01-Jan-2020	GBP				113	23,164,919		3,977,914
31-Dec-2019	GBP	2,508,323	5,032,633	487,193	345	69,494,757	-69,121,280	11,933,749
31-Dec-2018	GBP	11,086,173	12,808,408		114	23,164,919	-11,559,927	11,605,106
31-Dec-2017	GBP	1,181,768	2,149,403		51	8,305,187	-6,598,734	1,706,504

VALUATION EVENTS (BETA)

Year end	Currency	% Equity	Sum raised	Pre-Money Valuation*	Post-Money Valuation*	Enterprise Value**
31-Dec-2024	GBP	-50.00%	-31,159,782	93,479,346	62,319,564	73,791,544
31-Dec-2023	GBP	66.67%	62,319,564	31,159,782	93,479,346	61,568,779
01-Jan-2023	GBP	-100.00%	-31,159,782	62,319,564	31,159,782	45,920,991
31-Dec-2021	GBP	-50.00%	-31,159,782	93,479,346	62,319,564	76,170,102
31-Dec-2020	GBP	76.31%	70,314,314	21,828,345	92,142,659	56,074,831
01-Jan-2020	GBP	-205.31%	-46,330,070	68,896,009	22,565,939	44,476,813
31-Dec-2019	GBP	66.96%	46,330,069	22,864,190	69,194,259	39,231,976
31-Dec-2018	GBP	55.26%	14,859,795	12,029,358	26,889,153	13,325,285

* Average valuation during the period
** Estimated based on average Cash and Debt levels during period

DISPUTES

No disputes filed on www.disputesregister.org

COMPANY SECRETARY

Status	Name	Appointed on	Resigned on	Occupation	Nationality	All apointments (active/resigned)
Active	Philip James BOYD	15 Dec 2016	23 May 2025			1 - 0

DIRECTORS

Status	Name	Appointed on	Resigned on	Occupation	Nationality	All appointments (active/resigned)	Dissolved companies (rate)
Resigned	Bart DZIKOWSKI	01 Jan 2020	20 May 2021	None	Canadian	1 - 2	0 (0.0%)
Resigned	Johnathan Craig, Dr RICHARDSON	10 Sep 2019	20 May 2021	Investment Partner	British	1 - 2	0 (0.0%)
Resigned	Amit MUNSHI	02 Apr 2019	20 May 2021	Company Director	American,Swiss	1 - 2	0 (0.0%)
Resigned	Bobby G., Dr SONI	06 Apr 2018	10 Sep 2019	Investment Director	American	0 - 4	0 (0.0%)
Resigned	David MORRIS	06 Apr 2018	01 Jan 2020	Venture Partner, Novartis Venture Fund	American	0 - 1	0 (0.0%)
Resigned	Alexander Volker, Dr MAYWEG	06 Apr 2018	20 May 2021	Venture Partner	German	1 - 2	0 (0.0%)
Active	John William, Dr FORD	03 Nov 2016		Ceo	British	4 - 4	1 (12.5%)
Resigned	Robbie, Dr WOODMAN	05 May 2015	15 Feb 2018	Director Of Healthcare Ventures	British	1 - 5	1 (16.7%)
Resigned	Peter Michael, Dr FINAN	08 Dec 2014	20 May 2021	Venture Investor	British	12 - 7	4 (21.1%)
Resigned	Elizabeth ROPER	08 Dec 2014	02 Apr 2019	Fund Manager	Irish	4 - 2	0 (0.0%)
Resigned	Clive, Dr MCCARTHY	02 May 2014	08 Dec 2014	Scientist	British	1 - 1	0 (0.0%)
Resigned	Martin, Dr GOSLING	02 May 2014	06 Apr 2018	Scientist	British	0 - 1	0 (0.0%)
Resigned	Henry, Dr DANAHAY	02 May 2014	08 Dec 2014	Scientist	British	0 - 2	1 (50.0%)
Resigned	John Mervyn David, Professor STOREY	02 May 2014	08 Dec 2014	Scientist	British	0 - 2	0 (0.0%)

Number of active directors: 1
Average tenure of active directors: 8.6 years
Average tenure of resigned directors: 2.4 years
Average active director Dissolution Rate: 12.5%

DIRECTOR APPOINTMENTS IN OTHER COMPANIES

Name	John William, Dr FORD
ARIO PHARMA LIMITED (07391909) - Active	✔
ENTERPRISE THERAPEUTICS LTD (09022750) - Active	✔
GREYFORD CONSULTING LIMITED (09027093) - Active	✔
METRION BIOSCIENCES LTD (09669815) - Active	✔
NATRIUM THERAPEUTICS LIMITED (10203271) - Dissolved	✔
COMPLEMENT THERAPEUTICS LIMITED (12515463) - Active	✔
ENTERPRISE THERAPEUTICS HOLDINGS LIMITED (12868901) - Active	✔
TMEM16A LIMITED (12868907) - Active	✔

SHAREHOLDERS (BETA)

Shareholder name	Share class	Shares at confirmation date
Shareholder name	Share class	2020-05-02	2019-05-02	2018-05-02	2017-05-02	2016-05-02
VERSANT VENTURE CAPITAL VI, L.P.	SERIES B	3,600,667 23.6%	2,348,261 20.4%	2,348,261 20.5%	0 0%	0 0%
NOVARTIS BIOVENTURES LTD	SERIES B	2,258,782 14.8%	1,473,119 12.8%	1,473,119 12.9%	0 0%	0 0%
TOUCHSTONE INNOVATIONS BUSINESSES LLP	SERIES A	2,199,300 14.4%	2,199,300 19.1%	2,199,300 19.2%	1,649,475 41.9%	0 0%
EPIDAREX CAPITAL II, LP	SERIES A	2,199,300 14.4%	2,199,300 19.1%	0 0%	0 0%	0 0%
FORBION CAPITAL FUND III COOPERATIEF U.A.	SERIES B	1,837,143 12.0%	1,198,137 10.4%	1,198,137 10.5%	0 0%	0 0%
TOUCHSTONE INNOVATIONS BUSINESSES LLP	SERIES B	1,036,639 6.79%	1,036,639 9.01%	1,036,639 9.07%	0 0%	0 0%
IP2IPO PORTFOLIO (GP) LIMITED A/C IP2IPOPLP	SERIES B	552,874 3.62%	0 0%	0 0%	0 0%	0 0%
EPIDAREX CAPITAL II, LP	SERIES B	418,294 2.74%	0 0%	0 0%	0 0%	0 0%
DR DAVID G MORRIS	ORDINARY	252,631 1.65%	0 0%	0 0%	0 0%	0 0%
JOHN FLATLEY	SERIES A	221,416 1.45%	221,416 1.93%	221,416 1.94%	221,416 5.63%	0 0%
CLIVE MCCARTHY	ORDINARY	150,000 0.982%	150,000 1.30%	100,000 0.875%	100,000 2.54%	100,000 3.83%
AMIT MUNSHI	ORDINARY	126,315 0.827%	0 0%	0 0%	0 0%	0 0%
JOHN MERVYN DAVID STOREY	ORDINARY	100,000 0.655%	100,000 0.870%	100,000 0.875%	100,000 2.54%	100,000 3.83%
MARTIN GOSLING	ORDINARY	100,000 0.655%	100,000 0.870%	100,000 0.875%	100,000 2.54%	100,000 3.83%
HENRY DANAHAY	ORDINARY	100,000 0.655%	100,000 0.870%	100,000 0.875%	100,000 2.54%	100,000 3.83%
PETER MICHAEL FINAN	ORDINARY	52,637 0.345%	52,637 0.458%	52,637 0.461%	0 0%	0 0%
PHILIP JAMES BOYD	ORDINARY	15,792 0.103%	15,792 0.137%	15,792 0.138%	0 0%	0 0%
THE UNIVERSITY OF SUSSEX	ORDINARY	12,371 0.081%	12,371 0.108%	12,371 0.108%	12,371 0.315%	12,371 0.474%
DR HOLLY CHARLTON	ORDINARY	6,500 0.043%	6,500 0.057%	0 0%	0 0%	0 0%
JANET MAAS	ORDINARY	6,500 0.043%	0 0%	0 0%	0 0%	0 0%
DR ROY FOX	ORDINARY	6,500 0.043%	6,500 0.057%	0 0%	0 0%	0 0%
EDDIE FRENCH	ORDINARY	6,500 0.043%	0 0%	0 0%	0 0%	0 0%
DR SARAH LILLEY	ORDINARY	6,500 0.043%	6,500 0.057%	0 0%	0 0%	0 0%
KEITH OWEN	ORDINARY	6,500 0.043%	0 0%	0 0%	0 0%	0 0%
EPIDAREX CAPITAL IL, LP	SERIES B	0 0%	272,800 2.37%	0 0%	0 0%	0 0%
EPIDAREX CAPITAL II LP	SERIES A	0 0%	0 0%	2,199,300 19.2%	1,649,475 41.9%	0 0%
EPIDAREX CAPITAL II LP	SERIES B	0 0%	0 0%	272,800 2.39%	0 0%	0 0%
IMPERIAL INNOVATIONS BUSINESSES LLP	SERIES A	0 0%	0 0%	0 0%	0 0%	1,099,650 42.1%
EPIDAREX CAPITAL IT LP	SERIES A	0 0%	0 0%	0 0%	0 0%	1,099,650 42.1%

SHAREHOLDINGS (BETA)

no shareholding data

CONTROLLED COMPANIES / CONTROLLING ENTITIES

- >75%:Dr Philip James Boyd - ceased
>75%:Enterprise Therapeutics Holdings Limited (12868901 - United Kingdom) active
- 25-50%:Dr Elizabeth Ann Roper - active
- 25-50%:Dr Peter Michael Finan - active
- - 25-50%:Dr Elizabeth Ann Roper - active
  - 25-50%:Mr Andrew Sinclair Dunlop - active
  - 25-50%:Ms Kyparissia Katie Sirinakis - active
  >75%:Epidarex Management Ltd (Sc640075 - United Kingdom) active
- 25-50%:Mr Andrew Sinclair Dunlop - active
- 25-50%:Ms Kyparissia Katie Sirinakis - active
25-50%:Epidarex Capital Partners Limited (Sc437985 - United Kingdom) ceased
- - >75%:Ip Group Plc (04204490 - United Kingdom) active
  >75%:Top Technology Ventures Limited (01977742 - United Kingdom) active
25-50%:Ip2ipo Portfolio (Gp) Limited (10360684 - United Kingdom) ceased
- - >75%:Ip Group Plc (04204490 - United Kingdom) active
    >75%:Touchstone Innovations Plc (05796766 - United Kingdom) active
  >75%:Ip2ipo Innovations Limited (02060639 - United Kingdom) active
25-50%:Touchstone Innovations Businesses Llp (Oc333709 - United Kingdom) ceased

Controlling entities above

ENTERPRISE THERAPEUTICS LTD

no controlled companies

LATE PAYMENTS REPORT

This company has not filed any late payment reports possibly because it is not considered \'Large\'.

COURT CASES

No Court Cases found

PATENTS

No Patents found

COMPETITORS

(Based on Sic code: 72110 Research and experimental development on biotechnology)

Company	Registered Address	Company Number	YE Date	Revenue GBP	Net Profit GBP	Other SIC codes
ILLUMINA CAMBRIDGE LIMITED	19 GRANTA PARK, GREAT ABINGTON, CAMBRIDGE, CAMBRIDGESHIRE, ENGLAND, CB21 6DF	03625145	2017-12-31	2,114,848,000	422,140,000
IQVIA LTD.	3 FORBURY PLACE, 23 FORBURY ROAD, READING, UNITED KINGDOM, RG1 3JH	03022416	2017-12-31	1,123,545,000	198,818,000
AMGEN LIMITED	216 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE, CAMBRIDGESHIRE, ENGLAND, CB4 0WA	02354269	2017-12-31	238,931,000	9,488,000
GENOME RESEARCH LIMITED	WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS, HINXTON, SAFFRON WALDEN, ENGLAND, CB10 1SA	02742969	2018-09-30	144,812,000	55,555,000
COVANCE LABORATORIES LIMITED	OTLEY RD, HARROGATE, HG3 1PY	01171833	2017-12-31	111,519,000	16,839,000
ASTEX THERAPEUTICS LIMITED	436 CAMBRIDGE SCIENCE PARK, MILTON ROAD, CAMBRIDGE, CB4 0QA	03751674	2018-12-31	72,199,766	28,006,138
CELLTECH R&D LIMITED	208 BATH ROAD, SLOUGH, BERKSHIRE, SL1 3WE	01472269	2017-12-31	55,407,000	-5,338,000
QUOTIENT SCIENCES LIMITED	TRENT HOUSE MERE WAY, RUDDINGTON FIELDS BUSINESS PARK, RUDDINGTON, NOTTINGHAM, NG11 6JS	05221615	2018-03-31	43,379,000	7,170,000
CENTRE FOR PROCESS INNOVATION LIMITED	WILTON CENTRE, WILTON, REDCAR, CLEVELAND, TS10 4RF	05002194	2018-03-31	33,187,000	7,344,000	72190-Other research and experimental development on natural sciences and engineering 82990-Other business support service activities not elsewhere classified 85320-Technical and vocational secondary education
EVOTEC (UK) LIMITED	114 INNOVATION DRIVE, MILTON PARK, MILTON, ABINGDON, OXFORDSHIRE, OX14 4RZ	02674265	2017-12-31	31,859,000	1,599,000
ARC TRINOVA LIMITED	C/O QUOTIENT SCIENCES LIMITED TRENT HOUSE MERE WAY, RUDDINGTON FIELDS BUSINESS PARK, RUDDINGTON, NOTTINGHAM, ENGLAND, NG11 6JS	09767194	2017-12-31	8,422,519	0
CROWN BIOSCIENCE UK LIMITED	BUILDING 14 DODGEFORD LANE, OSGATHORPE, LOUGHBOROUGH, LEICESTERSHIRE, LE12 9TE	07109059	2017-12-31	2,819,775	0
INDUSTRIAL MICROBIOLOGICAL SERVICES LIMITED	ODD FELLOWS HALL, 118B OXFORD ROAD, READING, RG1 7NG	03264423	2018-01-31	1,005,784	0
THE BIO NANO CENTRE UNLIMITED	69 ONSLOW ROAD, ONSLOW ROAD, RICHMOND, ENGLAND, TW10 6QA	06389520	2018-02-28	974,607	0
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MEDEZRIN LTD.	71-75 SHELTON STREET, COVENT GARDEN, LONDON, UNITED KINGDOM, WC2H 9JQ	03340737	2018-03-31	170,000	0
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SEE-THROUGH SCIENTIFIC LIMITED	HARWOOD HOUSE, 43 HARWOOD ROAD, LONDON, ENGLAND, SW6 4QP	09410281	2017-12-31	76,514	0
DIAGNODUS LTD	ST JOHN'S INNOVATION CENTRE, COWLEY ROAD, CAMBRIDGE, ENGLAND, CB4 0WS	07600875	2019-04-30	63,322	0
FISHER STATISTICS CONSULTANCY LIMITED	10 HEDGEHOG CRESCENT, EDINBURGH, SCOTLAND, EH17 8XP	SC385170	2018-09-30	54,959	0	72200-Research and experimental development on social sciences and humanities 85600-Educational support services
SERNAT LIMITED	173 BROADWAY, DIDCOT, ENGLAND, OX11 8RZ	10372226	2017-09-30	51,815	0	72200-Research and experimental development on social sciences and humanities 86210-General medical practice activities
COULSON BIOINFORMATICS LTD	EXCHANGE BUILDING, 66 CHURCH STREET, HARTLEPOOL, UNITED KINGDOM, TS24 7DN	10904839	2018-08-31	48,628	0
IHG PHARMACO LIMITED	20-22 WENLOCK ROAD, LONDON, N1 7GU	05606880	2018-03-31	43,960	0
CALA PHARMA LIMITED	5 FARRIERS WAY, WINSFORD, ENGLAND, CW7 2TS	09883439	2017-11-30	35,084	0
GOLGENE TECHNOLOGIES LIMITED	9 CHURCH LANE, BISHOPSTON, SWANSEA, WALES, SA3 3JT	06069931	2019-01-31	35,041	0
GREENSTONE BIOLABS LTD	024, WESTBOURNE STUDIOS, ACKLAM ROAD, LONDON, ENGLAND, W10 5JJ	09874376	2017-11-30	33,043	0	72190-Other research and experimental development on natural sciences and engineering
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SP SCIENTIFIC SERVICES LTD	52 ANGEL HILL, SUTTON, UNITED KINGDOM, SM1 3EW	10312528	2018-08-31	15,229	0	72190-Other research and experimental development on natural sciences and engineering
CHEMOVATION LIMITED	WA10 1GH, 49 ARRIVATO PLAZA, HALL STREET, ST HELENS, UNITED KINGDOM, WA10 1GH	05316858	2018-12-31	12,182	0	74909-Other professional, scientific and technical activities not elsewhere classified
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RIOTECH PHARMACEUTICALS LIMITED	49 ARRIVATO PLAZA,, HALL STREET, ST HELENS, UNITED KINGDOM, WA10 1GH	04316377	2018-11-30	8,428	0
GENOMEX LTD	129C LIME WALK, HEADINGTON, OXFORD, ENGLAND, OX3 7AD	10356872	2018-09-30	7,923	0	72190-Other research and experimental development on natural sciences and engineering
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ALBANY CLINICAL CONSULTING LIMITED	7 NEW BROUGHTON, EDINBURGH, MIDLOTHIAN, UNITED KINGDOM, EH3 6PA	SC532187	2018-04-30	295	0
DYAX LTD	1 KINGDOM STREET, LONDON, ENGLAND, W2 6BD	08965623	2017-12-31	0	0	99999-Dormant Company
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CELL RESEARCH TECHNOLOGY LTD	32 FRIENDSHIP ROAD, BRISTOL, BS4 2RN	08192207	2018-08-31	0	0
DE NOVO PHARMACEUTICALS LIMITED	GILMARDE HOUSE, 47 SOUTH BAR STREET, BANBURY, OXFORDSHIRE, ENGLAND, OX16 9AB	03761178	2018-09-30	0	0
FERTILITY INNOVATIONS LIMITED	COOMBE HOUSE, BRADFORD PEVERELL, DORCHESTER, DORSET, DT2 9SE	07416896	2018-12-31	0	0
GARSINGTON TECHNOLOGIES LIMITED	4, THE GABLES, VALE OF HEALTH, HAMPSTEAD, LONDON, ENGLAND, NW3 1AY	08782927	2018-11-30	0	0
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PT VENTURES LIMITED	1A TOWER ROAD, DARTFORD, ENGLAND, DA1 2HE	09821026	2018-10-31	0	0
W C LEE LIMITED	94 HOWARD AVENUE, SLOUGH, BERKSHIRE, ENGLAND, SL2 1LA	09508311	2018-03-31	0	0
WALTERSTEAD LIMITED	ACADEMY HOUSE, SHEDDEN PARK ROAD, KELSO, ROXBURGHSHIRE, TD5 7AL	SC368318	2018-03-31	0	0	75000-Veterinary activities 82990-Other business support service activities not elsewhere classified
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LIQUIDATION RISK (BETA)

This company is Active. Statistically, Active companies have a low probability of being liquidated within a year.
Here are our probability predictions:

Basis	Liquidation within 3 months	Liquidation within 6 months	Liquidation within 12 months	Prediction confidence
ENTERPRISE THERAPEUTICS LTD	1.3%	2.3%	3.9%	Medium
Other companies Active in the same sector	1.2%	3.5%	7.4%	Medium


Expanded sample	1.3%	2.3%	3.9%	Medium
Age	0.4%	1.7%	3.3%	Medium
Company Type	0.7%	3.7%	7.4%	Medium
Accounts category	0.7%	2.2%	3.8%	Medium
Accounting Month	0.6%	2.4%	5.5%	Medium
Sic code count	0.7%	3.5%	7.0%	Medium